Cancer Chemical Biology Lab


  1. Maurya SK, Gollapalli DR, Kirubakaran S, Zhang M, Johnson CR, Benjamin NN, Hedstrom, L., Cuny GD. “Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase” J. Med. Chem. 2009, 52, 4623-4630.
  2. Macpherson I, Kirubakaran S, et al: “The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity” J. Am. Chem. Soc., 2010, 132 (4), 1230–1231).
  3. Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH: Sivapriya Kirubakaran, Suresh Kumar Gorla, Lisa Sharling, Minjia Zhang, Xiaoping Liu, Soumya S. Ray, Iain S. MacPherson, Boris Striepen, Lizbeth Hedstrom and Gregory D. Cuny, Bioorg. Med. Chem. Lett., 22 (5), 2012, 1985–1988
  4. Kinome-wide selectivity profiling of ATP-competitive mTOR (mammalian target of rapamycin) inhibitors and characterization of their binding kinetics: Liu Q , Kirubakaran S, Hur W, Niepel M, Westover K, Thoreen CC, Wang J, Ni J, Patricelli MP, Vogel K, Riddle S, Waller DL, Traynor R, Sanda T, Zhao Z, Kang SA, Zhao J, Look AT, Sorger PK, Sabatini DM, Gray NS, J Biol Chem. 2012, 287(13), 9742-52
  5. Biochemical, Cellular and in vivo characterization of Torin2, an ATP-competitive mTOR, ATM and ATR inhibitor: Qingsong Liu*, Chunxiao Xu*, Sivapriya Kirubakaran, Xin Zhang, Wooyoung Hur, Yan Liu, Nicholas P. Kwaitkowski, Jinhua Wang, Kenneth Westover, Peng Gao, Dalian Erica, Carson C. Thoreen, Seong A. Kang, Matthew P. Patricelli, Pasi A. Janne, Kwok Wong, David M. Sabatini, Nathanael S. Gray, Cancer Res. 2013, 73(8):2574-2586 ( * Equal first authors)
  6. Shaik, Althaf; Kirubakaran, Sivapriya and Thiruvenkatam, Vijay, “Crystal structure and Hirshfeld surface analysis of ethyl 5-phenylisoxazole-3-carboxylate”, Acta Crystallographica Section E: Crystallographic Communications, DOI: 10.1107/S2056989017003127, vol. 73, no. 4, pp. 531-534, 2017.
  7. Kirubakaran, Sivapriya and Thiruvenkatam, Vijay, “Diverse applications of nanotechnology in Biomedicine, Chemistry, and Engineering", in Oncology: Breakthroughs in Research and Practice, DOI: 10.4018/978-1-5225-0549-5.ch011, IGI Global, 2017, pp. 342-351, ISBN: 9781522505495.
  8. Purushothaman, Gayathri; Juvale, Kapil; Kirubakaran, Sivapriya and Thiruvenkatam, Vijay, “Water-mediated inter­molecular inter­actions in 1,2-O-cyclo­hexyl­idene-myo-inositol: a qu­anti­tative analysis”, Acta Crystallographica Section C: Structural Chemistry, DOI: 10.1107/S2053229616018581, vol. 73, no. 1, Jan. 2017.
  1. Chockalingam E,Kirubakaran S, Subramanian S, Chandrasekaran S. “Rice husk filtrate as a nutrient medium for the growth of desulfotomaculum nigrificans: Characterisation and sulfate reduction studies” Bioresource Tech. 2005, 96, 1880.
  2. Kirubakaran S, Chandrasekaran S. “Metathesis: A change-your-partners dance: Chemistry Nobel Prize-2005” Resonance 2006. (Invited Article)
  3. Kirubakaran K, Chandrasekaran S. “New conformationally locked thioderivatives of mannose: Synthesis, applications and mechanistic studies” Carbohyd. Res. 2006, 341, 2204.
  4. Kirubakaran S, Suguna P, Chandrasekaran S. “Novel tetraselenides of mannose: synthesis and mechanistic studies” Tetrahedron Lett. 2007, 48, 2091.
  5. Kirubakaran S, Suguna P, Shubasree S, Ramu Sridhar P, Chandrasekaran S. “Novel chalcogenides of thymidine and uridine: Synthesis, properties and applications” Carbohyd. Res. 2007, 342, 1151.
  6. Kirubakaran S, Sridhar H, Suhas VL, Chandra N, Chandrasekaran S. “Conformationally locked thiosugars as potent α- mannosidase inhibitors” Bioorg. Med. Chem. 2007, 15, 5659.
  7. Kirubakaran S, Suguna P, Bannerji A, Rao DN, Chandrasekaran S. “Facile one pot synthesis of new thio and seleno urea derivatives: A new class of potent urease inhibitors” Bioorg. Med. Chem. Lett. 2007, 17, 6387.
  8. Mitra A, Kirubakaran S, Anilkumar. “Experimental implementation of a 3-qubit quantum game with corrupt source using nuclear magnetic resonance quantum information processor” J. Mag. Res. 2007, 187, 306.