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Biological Engineering Sharad Gupta |
Sharad Gupta
Assistant Professor |
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M.Sc.(Integrated, 5yr.): IIT Kanpur, 2003
Ph.D.: University of Pittsburgh, 2009 |
Email: sharad@iitgn.ac.in |
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| Research Interest |
- Protein misfolding in Alzheimer’s and Huntington’s Diseases.
- UPS impairment in neurodegenerative disorders.
- Targeting shared cellular pathways for therapeutic intervention.
- Novel antimicrobial peptidomimetic scaffolds.
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| Work Experience |
- Assistant Professor, Indian Institute of Technology Gandhinagar (July 2011 to Present)
- Post Doctoral Fellow, Department of Chemical and Biomolecular Engineering, University of Delaware (Aug 2010 - June 2011)
- Post Doctoral Researcher, Department of Chemistry, Temple University (Sept 2009-July 2010)
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| Selected Recent Publications |
- Gupta, S., Colby, D. W. “Protein misfolding detected early in the pathogenesis of a transgenic mouse model of Huntington's disease using an amyloid seeding assay” Journal of Biological Chemistry, December 2011, (early view).
- Gupta, S., Schafmeister, C. E. “Synthesis of a Carboxylate Functionalized Bis-Amino Acid Monomer.” J. Org. Chem. 2009, 74, 3652-3658.
- Schafmeister, C. E., Brown, Z. Z., Gupta, S. “Shape programmable Macromolecules.” Acc. Chem. Res. 2008, 41, 1387-1398.
- Gupta, S., Macala, M., Schafmeister, C. E. “Synthesis of Structurally Diverse Bis-peptide Oligomers.” J. Org. Chem. 2006, 71, 8691-8695.
- Gupta, S., Das, B. C., Schafmeister, C. E. “Synthesis of a Pipecolic Acid-Based Bis-amino Acid and Its Assembly into a Spiro Ladder Oligomer.” Org. Lett. 2005, 7, 2861-2864.
- Khan, F. A., Dash, J., Sahu, N., Gupta, S. “Regio and Diastereoselective reduction of Nonenolizable -Diketones to Acyloins mediated by Indium metal.” Org. Lett. 2002, 4, 1015-1018.
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