Research Interests   |  Publications

Aiming to be a center for pioneering research and innovation the chemistry discipline at IIT-Gn is home to fundamental and applied research in the areas of asymmetric catalysis, applied biochemistry, drug discovery, medicinal chemistry, organic photochemistry, synthetic pigments, materials catalysis and computational chemistry. The research lines in the discipline are driven the faculty who bring with them years of research experience and international exposure.

With a strong focus on interdisciplinary research the discipline is engaged in active collaboration with other disciplines at IIT-Gn and institutes across India and around the world.

Iti Gupta (Synthetic Pigments)

Our group at IIT Gandhinagar is involved in the synthesis of porphyrin derivatives (such as Corroles and N-Confused porphyrins) to mimic energy donor-acceptor (D-π-A) systems. We are also pursuing synthesis of various Boron based dypyrrin dyes for Near IR absorption and emission properties. The ultimate goal is to prepare water soluble novel porphyrin derivatives/ boron dipyrrin dyes for biological applications. The NIR dyes and porphyrin derivatives with appropriate functionality have potential applications as metal/anion sensors in various media as well as sensitizers for Dye Sensitized Solar Cells (DSSC).

Sriram Kanvah Gundimeda (Fluorescent Materials)

Our core area is development of novel π-conjugated fluorescent materials for organic electronic and biological applications. Our current research interests involve design and synthesis of fluorescent bioconjugates and photoactive selfassemblies and substrates that exhibit aggregation induced enhanced emission. The research involves a combination of synthetic organic chemistry and instrumental analysis involving optical absorption and emission techniques along with electron microscopy.

Sudhanshu Sharma (Materials Catalysis)

Our research focuses in on two different aspects of heterogeneous catalysis:

  1. Gas-solid heterogeneous catalysis- We make a number of solid state compounds and use them for various gas-solid reactions such as dry reforming reaction, CO2 methanation reaction, NOx reduction and methane activation to name a few. These studies involve synthesizing solid materials and characterizing them completely using X-ray diffraction, IR spectroscopy, X-ray photoelectron spectroscopy and transmission electron microscopy (TEM). These well characterized materials are used for above mentioned reaction. This is our quest to find the active catalyst for these reactions for application related to energy and environment.
  2. Electrochemistry and electrocatalysis- We have been extensively doing research in this area. Our main focus is CO2 electro-reduction to make useful. Other than this we have strong fundamental interest in understanding the metal and support interaction using electrochemistry of solid and conducting metal oxides. How ions and metal behave electrochemically different is what we have been exploring currently.

Sivapriya Kirubakaran (Drug discovery and Medicinal chemistry)

Our research group works on the chemical biology of diseases especially cancer. Our lab focus is to use small molecules as a powerful tool to study cancer related proteins to discover new age cancer therapeutics. We work on the interface of chemistry and biology which includes chemical synthesis, biochemistry & cell biology.

Currently we are focusing on the Kinases involve in DNA Repair mechanism like ATR/ATM. Our long-term goal would be to make affordable medicines for cancer particularly for stomach and Breast Cancer.

Chandrakumar Appayee (Asymmetric Catalysis)

Asymmetric synthesis is one of the most demanding areas of research in pharmaceutical industry due to the importance of single enantiomers as drug molecules. Our group focuses on asymmetric catalysis for the synthesis of enantiomerically pure bio-active small molecules. We are interested on the development of organocatalysis to meet various challenges present in asymmetric synthesis. For this purpose, we design novel catalysts and develop new methodologies to improve chiral selectivity’s in the existing and new organic reactions. We use chiral organocatalysts that are having different catalophores and chirophores to activate substrates for achieving high enantioselectivity. We are also interested in devising a supramolecular host-guest catalytic system for the useful asymmetric organic transformations.

Sairam Swaroop Mallajosyula (Computational Chemistry)

Our research group uses computational tools to investigate the relationship of structure and dynamics to the function of biomolecules. We primarily use molecular dynamics simulations and density functional calculations to explore the energetics of the system. Our current research interests involve the study of glycoproteins and modified nucleic acids structures. The group is also involved in development of empirical force field parameters and enhanced conformational sampling methods.

Saumya Khatua (Plasmonics)

Our group is interested in various applications of plasmonic nanoparticles and their assemblies. Particularly, we focus on: (a) plasmon-enhanced spectroscopy and (b) sub-diffraction guiding of light. We are also interested in developing new methods for preparing nanoparticle assemblies with narrow yet tunable interparticle spacings.

Arnab Dutta (Biomimetic Chemistry)

Renewable energy resources such as solar, wind, or tidal have emerged as one of the best alternatives for universally used carbon-based fossil fuels. Two steps are essential for proper utilization of these renewable energy resources on the current scale of fossil fuels. They are (1) efficient storage of these intermittent energy resources and (2) proper extraction of that stored energy for future usage. Several combinations of small molecules can be employed for this energy transformation process. However, all of them require an electrocatalyst to facilitate the chemical transformations. In my research group our goal is to develop such electrocatalysts for small molecule activation such as H2, O2, CO2, and CO.

For this purpose, our inspiration will be the enzymes, the perfect catalysts found in nature. Direct usage of these enzymes is difficult due to their instability under harsher chemical conditions demanded for the practical applications. These enzymes evolved over millions of years and have very complex structures. We will try to understand the basic blueprint of their architecture and will include them in our own synthetic catalyst framework. The two significant segments of our design will be: (1) the primary coordination core containing the organometallic core (mimicking enzyme active site) and (2) the amino acid based outer coordination sphere (modeling the protein scaffold found in enzymes).